- Antibody Type:Primary
- Antigen Name:Ribonuclease A2
- Antigen Symbol:RNASE2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:6036
- Antigen Synonyms:Rnase-A2|EDN|Ribonuclease,RNase A Family,2|Liver,Eosinophil-Derived Neurotoxin|Rnase2|Ribonuclease US|MNon-secretory ribonuclease
- Amino Acid Number:28 - 161
- UniProtKB:P10153
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:32 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, –20 ℃ for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C.
- Immunogen:Recombinant RNASE2 (Lys28~Ile161)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAD169HU1
- Packaging:Vial
Polyclonal Antibody to Ribonuclease A2 (RNASE2), derived from recombinant RNASE2 (Lys28~Ile161), is reactive with Human/Mouse.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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Eosinophil-derived neurotoxin is a distinct cationic protein of the eosinophil's large specific granule known primarily for its ability to induce ataxia, paralysis, and central nervous system cellular degeneration in experimental animals (Gordon phenomenon). Rosenberg et al. (1989) isolated a 725-bp cDNA clone for EDN. The open reading frame encodes a 134-amino acid polypeptide with a molecular mass of 15.5 kD and a 27-residue N-terminal hydrophobic leader sequence. The sequence of the mature polypeptide was identical to that reported for human urinary ribonuclease and to the N-terminal sequence of human liver ribonuclease. Similarities to the ribonucleases of pancreas and angiogenin indicate that EDN belongs to the ribonuclease multigene family. This gene is also symbolized RNS2 for ribonuclease 2.
Type: Primary
Antigen: RNASE2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse