Specifications
- Antibody Type:Primary
- Antigen Name:Immune Receptor Expressed On Myeloid Cells 1
- Antigen Symbol:IREM1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:246746
- Antigen Synonyms:CD300LF|CMRF35-Like Molecule 1|NKIR|NK inhibitory receptor|Immunoglobulin superfamily member 13|CLM1|CD300 Antigen Like Family Member F|IGSF13|CD300f
- UniProtKB:Q6SJQ7
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Storage Temperature:Store at 2...8 °C for frequent use, –20 ℃ for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C.
- Immunogen:Recombinant IREM1
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB377MU1
- Packaging:Vial
Specifications
About this item
Polyclonal Antibody to Immune Receptor Expressed On Myeloid Cells 1 (IREM1), derived from recombinant IREM1, is reactive with Human/Mouse.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells.The predicted 290-amino acid protein shares 32% amino acid identity with CMRF35 (CD300C). It contains a 23-residue signal peptide, a 132-residue extracellular region, a 23-residue transmembrane domain, and a 112-residue cytoplasmic region. The extracellular region has a typical Ig-like domain and an N-linked glycosylation site, and the cytoplasmic region has 2 immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and an ITIM-like motif. Northern blot analysis revealed abundant expression of a 1.9-Kb transcript in spleen, peripheral blood leukocytes, and lung, but only weak or no expression in all other tissues examined. RT-PCR analysis detected expression in DCs, monocytes, and monocytic cell lines, but not in T or B cells.
Type: Primary
Antigen: IREM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse