- Antibody Type:Primary
- Antigen Name:Histone H3
- Antigen Symbol:H3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Rabbit,Horse,Monkey,Chicken,Human,Bovine,Dog,Rat,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:8350
- Amino Acid Number:1 - 136
- UniProtKB:P68431
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:18 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, –20 ℃ for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.84 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C.
- Immunogen:Recombinant H3 (Met1~Ala136)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAA285MI1
- Packaging:Vial
Polyclonal Antibody to Histone H3 (H3), derived from recombinant H3 (Met1~Ala136), is reactive with Human/Mouse/Rat/Rabbit/Simian/Dog/Bovine/Horse/Chicken.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
- All in stock and fast global delivery
- 100% Quality and service satisfaction guarantee
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. The term 'Histone H3' alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Mammalian cells have three known sequence variants of histone H3. These are denoted as Histone H3.1, Histone H3.2 and Histone H3.3 but are highly sequence conserved differing only by a few amino acids.
Type: Primary
Antigen: H3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Rabbit, Simian, Dog, Bovine, Horse, Chicken