Specifications
- Antibody Type:Primary
- Antigen Name:Surfactant Protein C
- Antigen Symbol:SP-C
- Clonality:Monoclonal
- Clone:D3
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Human
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:6440
- Antigen Synonyms:Pulmonary surfactant-associated proteolipid SPL(Val)|PSP-C|Pulmonary Surfactant Protein C|SPC|Surfactant Associated Protein C|SP5|SFTP2|SFTPC
- Amino Acid Number:24 - 191
- UniProtKB:P11686
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Molecular Weight:48 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:1 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant SP-C(Phe24~Ile191)
- Purification:Protein A + Protein G affinity chromatography
- Cat. No.:MSPP-MAB623HU2
- Packaging:Vial
Specifications
About this item
Monoclonal Antibody to Surfactant Protein C (SP-C), derived from recombinant SP-C(Phe24~Ile191), is reactive with Human.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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SP-C is a fragment of a much larger precursor protein of 21 kD. The precursor contains an exceedingly hydrophobic region of 34 amino acids that comprises most of the mature SP C, and a unique poly-valine domain.Pulmonary surfactant-associated protein C is a membrane protein which manufactures surfactant.Humans and animals born lacking SP-C tend to develop progressive interstitial pneumonitis.The SFTPC gene encodes pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. It is produced exclusively by type II alveolar epithelial cells in the lung. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung.
Type: Primary
Antigen: SP-C
Clonality: Monoclonal
Clone: D3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: Human