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Anti-Amylin Mouse Monoclonal Antibody [clone: C2]
Anti-Amylin Mouse Monoclonal Antibody [clone: C2]
  MSPP-MAA812HU2
 :  CLOUD-CLONE CORP MS
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Anti-Amylin Mouse Monoclonal Antibody [clone: C2]
  MSPP-MAA812HU2
 :  CLOUD-CLONE CORP MS
 :  MAA812HU22

 

  • Antibody Type:
    Primary
  • Antigen Name:
    Amylin
  • Antigen Symbol:
    Amylin
  • Clonality:
    Monoclonal
  • Clone:
    C2
  • Conjugation:
    Unconjugated
  • Host:
    Mouse
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG2a kappa
  • Reactivity:
    Human
  • Western Blot:
    Yes
  • Size:
    200 µl
  • Cross Adsorption:
    No
  • Form:
    Liquid
  • Gene ID:
    3375
  • Antigen Synonyms:
    IAP|Islet Amyloid Polypeptide|Diabetes-associated peptide|DAP|IAPP|Insulinoma Amyloid Polypeptide
  • Amino Acid Number:
    34 - 50
  • UniProtKB:
    P10997
  • Storage Buffer:
    0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
  • Storage Temperature:
    Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
  • Concentration:
    1 mg/ml (for reference only)
  • Shipping Temperature:
    Shipped on blue ice at 4 °C
  • Immunogen:
    Recombinant Amylin(Lys34~Val50)
  • Purification:
    Protein A + Protein G affinity chromatography
  • Cat. No.:
    MSPP-MAA812HU2
  • Packaging:
    Vial

 

 

Monoclonal Antibody to Amylin, derived from recombinant Amylin(Lys34~Val50), is reactive with Human.

  • High specificity, affinity, and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
  • All in stock and fast global delivery
  • 100% Quality and service satisfaction guarantee

Islet, or insulinoma, amyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish.,Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in insulin-producing beta cells, an effect that may be relevant to the development of type 2 diabetes. Finally, a recent study reported a synergistic effect for weight loss with leptin and amylin coadministration in diet-induced obese rats by restoring hypothalamic sensitivity to leptin .

 : For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: Amylin
Clonality: Monoclonal
Clone: C2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: Human