Specifications

Antibody Type:
Primary
Antigen Name:
Quinolinic Acid
Antigen Symbol:
QA
Clonality:
Polyclonal
Conjugation:
Unconjugated
ELISA:
Yes
Host:
Rabbit
ImmunoChemistry:
Yes
ImmunoPrecipitation:
Yes
Isotype:
IgG
Reactivity:
Multiple
Size:
200 µl
Cross Adsorption:
No
Form:
Liquid
Antigen Synonyms:
QUIN|Pyridine-2,3-Dicarboxylic Acid
Storage Buffer:
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
Molecular Weight:
167.1 Da
Storage Temperature:
Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
Concentration:
0.5 mg/ml (for reference only)
Shipping Temperature:
Shipped on blue ice at 4 °C
Immunogen:
OVA conjugated QA
Purification:
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Cat. No.:
MSPP-PAK552GE1
Packaging:
Vial

Specifications

About this item

Polyclonal Antibody to Quinolinic Acid (QA), derived from OVA conjugated QA, is reactive with General species.

High specificity, affinity, and purity
Extensive validation and batch-to-batch consistency
Diverse range of conjugated and custom options
Comprehensive validation data and documentation
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Quinolinic acid is a dicarboxylic acid with a pyridine backbone. It may be prepared by the oxidation of quinoline. Quinolinic acid is a downstream product of the kynurenine pathway, which metabolizes the amino acid tryptophan. It acts as an NMDA receptor agonist. Quinolinic acid has a potent neurotoxic effect. Studies have demonstrated that quinolinic acid may be involved in many psychiatric disorders, neurodegenerative processes in the brain, as well as other disorders. Within the brain, quinolinic acid is only produced by activated microglia and macrophages. Quinolinic acid is a byproduct of the kynurenine pathway, which is responsible for catabolism of tryptophan in mammals. Quinolinic acid is unable to pass through the blood-brain barrier (BBB) and must be produced within the brain microglial cells or macrophages that have passed the BBB.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: QA
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: General species