- Antibody Type:Primary
- Antigen Name:Angiotensin 1-7
- Antigen Symbol:Ang1-7
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Horse,Sheep,Human,Dog,Rat,Mouse
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:183
- Amino Acid Number:34 - 40
- UniProtKB:P01019
- Storage Buffer:0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant Ang1-7(Asp34~Pro40)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAS085MI8
- Packaging:Vial
Polyclonal Antibody to Angiotensin 1-7 (Ang1-7), derived from recombinant Ang1-7(Asp34~Pro40), is reactive with Human/Mouse/Rat/Dog/Sheep/Horse.
- High specificity, affinity, and purity
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Angiotensin(1-7) (Ang1-7) acting at the level of the rostral ventrolateral medulla (RVLM) affects arterial pressure. Astroglia are a plausible cellular target of Ang1-7 in RVLM. Astrocytic responsiveness to Ang1-7 is reduced in SHR. Ang1-7 modulates astrocytic signalling which in vivo may affect local metabolism and microcirculation, resulting in changes in activity of RVLM pre-sympathetic neurones and hence blood pressure.,Ang1-7 is an important component of the central renin-angiotensin system and affects haemodynamics when injected into the RVLM. Effect of Ang1-7 could be blocked by co-application of its antagonist, A779 (200 nM) but not losartan (1 µM). non-CA neurones and glia in RVLM are the primary targets for Ang1-7 and its effect on [Ca2+]i in non-CA neurones is enhanced in SHR.
Type: Primary
Antigen: Ang1-7
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human;Mouse;Rat;Dog;Sheep;Horse