- Antibody Type:Primary
- Antigen Name:Uridine Phosphorylase 1
- Antigen Symbol:UPP1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Western Blot:Yes
- Size:200 µl
- Cross Adsorption:No
- Form:Liquid
- Gene ID:22271
- Antigen Synonyms:UPASE|UDRPASE|UP
- Amino Acid Number:1 - 277
- UniProtKB:P52624
- Storage Buffer:PBS, pH 7.4, containing 0.02% NaN₃, 50% glycerol
- Molecular Weight:34 kDa
- Storage Temperature:Store at 2...8 °C for frequent use, −20 °C for 24 months. Avoid repeated freeze-thaw cycles.
- Concentration:0.5 mg/ml (for reference only)
- Shipping Temperature:Shipped on blue ice at 4 °C
- Immunogen:Recombinant UPP1(Met1~Leu277)
- Purification:Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- Cat. No.:MSPP-PAB811MU1
- Packaging:Vial
Polyclonal Antibody to Uridine Phosphorylase 1 (UPP1), derived from recombinant UPP1(Met1~Leu277), is reactive with Mouse/Rat.
- High specificity, affinity, and purity
- Extensive validation and batch-to-batch consistency
- Diverse range of conjugated and custom options
- Comprehensive validation data and documentation
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The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate.,The recombinant UP expressed in COS-7 cells demonstrated specific enzyme activity with uridine as the substrate; this activity was inhibited by a competitive inhibitor. Northern blot analysis with the cDNA as a probe demonstrated high levels of mRNA expression in several tumor cell lines but a very low level in a normal cell line.
Type: Primary
Antigen: UPP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse;Rat