About this item
Assay-specific crystal flex probes and primers for the detection of BRCA1/RAD51C/GSTP1 methylation and its positive control. The BRCA1/RAD51C/GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the BRCA1, RAD51C, and GSTP1 promoter using the ruby chip. Methylation of the BRCA1, RAD51C, and GSTP1 affects DNA repair mechanisms crucial for genome stability and dysregulation of detoxification pathways, both contributing to tumor initiation, progression, and drug resistance.
- Ready-to-use assay reagents to detect multiple targets in a single reaction
- Crystal flex probe detection chemistry for flexible assay configuration
- Same set of crystal universal reporters to detect any target in different assays
Wet lab tested
Compatibility: Nio™ Digital PCR, Prism6, ruby chip
Channels: Blue; Teal; Green; Yellow; Red; Infra-Red
Required reagents: Crystal universal reporter 7 and naica® PCR MIX 10X
Targets: BRCA1/RAD51C/GSTP1 promoter methylation
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Related Information
Stilla Technologies Crystal Flex Probes and Crystal Universal Reporters