Assay-specific Crystal Flex Probes and primers for the detection of ESR1 mutations and its positive control. ESR1 (17 mutations) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 17 mutations in the ESR1 gene using the Ruby Chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.

• Ready-to-use assay reagents to detect multiple targets in a single reaction
• Crystal Flex Probe detection chemistry for flexible assay configuration
• Same set of crystal universal reporters to detect any target in different assays
• High multiplexing with low price per point

Wet lab tested
Compatibility: Nio™ Digital PCR, Prism6, ruby chip
Channels: Green, yellow, red, infrared, blue, teal, LSSD
Required reagents: Crystal universal reporter 7 and naica® PCR MIX 10X
Target ESR1: E380Q/V422del/S463P/D538G/D538N/L536H/L536P/L536Q_delinsAG/L536R/Y537C/Y537D/Y537H/Y537N/Y537N_delinsTA/Y537S/Y537S_delinsAG/Y537S_ delinsCA