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Human Recombinant HGF (CHO-expressed)
Human Recombinant HGF (CHO-expressed)
  MSPP-780191
 :  
Human Recombinant HGF (CHO-expressed)
  MSPP-780191
 :  78019.1
 :  

 

  • Protein/Peptide Type:
    Recombinant
  • Source:
    CHO cells
  • Species:
    Human
  • Size:
    10 µg
  • Protein Synonyms:
    DFNB39|FTCF|Fibroblast-derived tumor cytotoxic factor|Hepapoietin A|HPTA|Lung fibroblast-derived mitogen|Scatter factor|SF
  • Protein/Peptide Name:
    HGF
  • Purity:
    ≥95%
  • Cat. No.:
    MSPP-780191

 

 

Hepatocyte growth factor/scatter factor (HGF/SF) is a pleiotropic growth factor that promotes proliferation, motility, survival, and differentiation. HGF binds and promotes the dimerization and activation of the receptor tyrosine kinase c-MET, and stimulates PI3K/AKT, FAK, JNK, and ERK1/2 signaling (Organ and Tsao). HGF stimulates migration of cells during embryogenesis, induces cell motility and scattering of epithelial cells, and regulates epithelial-mesenchymal transition. It is a chemoattractant for motor neurons, and regulates the development of sensory, sympathetic, parasympathetic, and cortical neurons as well as the proliferation of oligodendrocytes and glial development. Additionally, HGF is cytoprotective and regulates liver growth and regeneration (Nakamura et al.).

 : Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').