Scale up from analytical to a preparative LC method with Thermo Scientific™ Hypersil™ PREP BDS C8 reversed phase preparative HPLC column.

• Successful retention and separation of moderately hydrophobic analytes
• Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns
• Base deactivated silica
• C8 (USP L7) selectivity
• pH stable from 2 to 8
• Maximum temperature of 60 °C
• Higher analytical throughput compared to C18 alkyl chain chemistry
• Quicker compound elution due to reduced hydrophobic interactions

These columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. With similar selectivity to C18 columns and predictable elution order, C8 columns with base deactivation for reduced silanol activity are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations.

Standard Threaded and Standard Flange Hardware; Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. Standard threaded hardware for column int.Ø <40 mm. Standard flange hardware for column int.Ø. ≥40 mm. Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware; Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. Compatible with SFC and is available in dimensions up to 50 mm int.Ø. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Preparative HPLC column hardware options - based on column inner Ø (int.Ø.) and column performance needs.