Specifications
- Antibody Type:Primary
- Antigen Name:JNK1(Thr183) + JNK2(Thr183) + JNK3(Thr221)
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG (H, L)
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µl
- Gene ID:5599
- Storage Buffer:0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
- Molecular Weight:50 kDa
- Storage Temperature:Store at –20 °C for 12 months.
- Concentration:1 µg/µl
- Purification:Purified by protein A
- Cat. No.:77438-274
- Packaging:Vial
Specifications
About this item
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq, Jun 2013).
Type: Primary
Antigen: JNK1(Thr183) + JNK2(Thr183) + JNK3(Thr221)
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human, Mouse, Rat