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Specifications
- Antibody Type:Primary
- Antigen Name:Complement C5 beta chain
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG (H, L)
- Reactivity:Human
- Size:100 µl
- Environmentally Preferable:
- Gene ID:727
- Storage Buffer:0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
- Molecular Weight:72
- Storage Temperature:Shipped at 4 ℃. Store at −20 °C for one year. Avoid repeated freeze/thaw cycles.
- Concentration:1 µg/µl
- Purification:Purified by Protein A
- Cat. No.:77436-948
- Packaging:Vial
Specifications
About this item
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).
Type: Primary
Antigen: Complement C5 beta chain
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human