Specifications
- Antigen Name:Denosumab
- Clonality:Monoclonal
- Clone:2H7
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Size:40 μg
- Cross Adsorption:No
- Form:Lyophilized
- Storage Buffer:This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide
- Storage Temperature:The lyophilized product remains stable up to 1 year at −20 °C from date of receipt. Upon reconstitution, it can be stored for 2 - 3 weeks at 2...8 °C or for up to 12 months at −20 °C or below. Avoid repeated freezing and thawing cycles
- Concentration:Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
- Immunogen:Denosumab
- Cat. No.:77007-516
- Packaging:Vial
Specifications
About this item
Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface. Anti-Denosumab Antibody (2H7), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Denosumab.
- High specificity
- High affinity
- High stability
GenScript has developed a broad range of off-the-shelf anti-idiotype antibodies against blockbuster drugs to help accelerate your research of biosimilars.
Type:
Antigen: Denosumab
Clonality: Monoclonal
Clone: 2H7
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: