- Antibody Type:Primary
- Antigen Name:ANKRD6
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µl
- Epitope:421-520/727
- Form:Liquid
- Antigen Synonyms:ANKR6_HUMAN|Ankyrin repeat domain-containing protein 6|ANKRD 6|ankyrin repeat domain 6|Diversin
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- Storage Temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ANKRD6/Diversin
- Purification:Purified by Protein A
- Cat. No.:76109-612
- Packaging:Vial
Diversin, also known as ANKRD6 (ankyrin repeat domain 6), is a 727 amino acid protein that contains eight ankyrin repeats and belongs to the ankyrin repeat domain protein family. Members of the ankyrin repeat domain family facilitate protein-protein interactions and function as adaptors of signaling pathways. Expressed in a developmentally-regulated manner and at highest levels in the brain, Diversin is believed to play a role in brain development. Via its ankyrin repeats, Diversin can directly interact with Dvl (dishevelled), an interaction that is essential for the activation of noncanonical Wnt signaling. In addition, Diversin contains a C-terminal domain that binds Axin/Conductin and a casein kinase-binding domain in its central region that specifically binds casein kinase I?. Through the action of these additional domains, Diversin may also facilitate canonical Wnt signaling. Due to alternative splicing events, three Diversin isoforms exist.
Type: Primary
Antigen: ANKRD6
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 421-520/727
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat