Specifications
- Antibody Type:Primary
- Antigen Name:CLEC 4E
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat
- Western Blot:Yes
- Size:100 µl
- Epitope:51-150/219
- Form:Liquid
- Gene ID:26253
- Antigen Synonyms:C type lectin superfamily member 9|C type lectin domain family 4 member E|MINCLE|CLEC 4E|CLC4E_HUMAN|C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9|CLEC4E Clec4e|Macrophage-inducible C-type lectin|C-type lectin superfamily member 9|Macrophage inducible C type lectin|C-type lectin domain family 4 member E|CLECSF9
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- Molecular Weight:25 kDa
- Storage Temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76107-474
- Packaging:Vial
Specifications
About this item
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
Type: Primary
Antigen: CLEC 4E
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-150/219
Host: Rabbit
Isotype: IgG
Reactivity: Human; Rat