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Anti-CLEC 4E Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-CLEC 4E Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # 76107-474
Supplier:  Bioss
Anti-CLEC 4E Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # 76107-474
Supplier:  Bioss
Supplier Number:  BS-8541R-A750

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    CLEC 4E
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Flow Cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat
  • Western Blot:
    Yes
  • Size:
    100 µl
  • Epitope:
    51-150/219
  • Form:
    Liquid
  • Gene ID:
    26253
  • Antigen Synonyms:
    C type lectin superfamily member 9|C type lectin domain family 4 member E|MINCLE|CLEC 4E|CLC4E_HUMAN|C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9|CLEC4E Clec4e|Macrophage-inducible C-type lectin|C-type lectin superfamily member 9|Macrophage inducible C type lectin|C-type lectin domain family 4 member E|CLECSF9
  • Modification:
    Unmodified
  • Storage Buffer:
    Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
  • Molecular Weight:
    25 kDa
  • Storage Temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping Temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E
  • Tested Applications:
    ICC
  • Purification:
    Purified by Protein A
  • Cat. No.:
    76107-474
  • Packaging:
    Vial

Specifications

About this item

C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Type: Primary
Antigen: CLEC 4E
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-150/219
Host: Rabbit
Isotype: IgG
Reactivity: Human; Rat