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Specifications
- Antibody Type:Primary
- Antigen Name:AMPK beta 1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Other,Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µl
- Form:Liquid
- Gene ID:5564
- Antigen Synonyms:5'-AMP-activated protein kinase subunit beta-1|AMPK subunit beta-1|AMPK|HAMPKb|PRKAB1|AMPKb
- Modification:Phosphorylation (Ser182)
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Molecular Weight:30 kDa
- Storage Temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human AMPK beta 1 around the phosphorylation site of Ser182
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76083-298
- Packaging:Vial
Specifications
About this item
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Type: Primary
Antigen: AMPK beta 1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat; Others