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Anti-MAP1A/MAP1B LC3 A/B Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anti-MAP1A/MAP1B LC3 A/B Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # 76082-992
Supplier:  Bioss
Anti-MAP1A/MAP1B LC3 A/B Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Catalog # 76082-992
Supplier:  Bioss
Supplier Number:  BS-2912R-A680

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    MAP1A/MAP1B LC3 A/B
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 680
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rabbit,
    Human,
    Rat,
    Mouse
  • Western Blot:
    Yes
  • Size:
    100 µl
  • Epitope:
    21-121/121
  • Form:
    Liquid
  • Gene ID:
    81631, 84557
  • Antigen Synonyms:
    MAP1A/1BLC3|Autophagy related ubiquitin like modier LC3 B|MAP1 light chain 3 like protein 1|MAP LC3 beta|MAP1LC3B|Autophagy related protein LC3 B|Microtubule associated proteins 1A/1B light chain 3A|MAP1BLC3|Autophagy related ubiquitin like modier LC3 A|Microtubule associated protein 1 light chain 3 beta|MAP1ALC3|Microtubule associated proteins 1A/1B light chain 3B.microtubule-associated proteins 1A/1B light chain 3 beta 2|MAP1A/MAP1B LC3 B|Microtubule associated protein 1 light chain 3 alpha|MAP1LC3A|MAP1A/1B light chain 3 B|LC3|MAP1 light chain 3 like protein 2|Microtubule associated proteins 1A/1B light chain 3|MAP1A/MAP1B LC3 A|Autophagy related protein LC3 A|MAP1A/1B light chain 3 A
  • Modification:
    Unmodified
  • Storage Buffer:
    Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
  • Molecular Weight:
    13 kDa
  • Storage Temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping Temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B
  • Tested Applications:
    ICC
  • Purification:
    Purified by Protein A
  • Cat. No.:
    76082-992
  • Packaging:
    Vial

Specifications

About this item

A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.

Type: Primary
Antigen: MAP1A/MAP1B LC3 A/B
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 21-121/121
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat; Rabbit