Specifications
- Antibody Type:Primary
- Antigen Name:CCL4
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rabbit,Human,Mouse
- Western Blot:Yes
- Size:100 µl
- Epitope:26-92/92
- Form:Liquid
- Gene ID:6351
- Antigen Synonyms:MIP-1_|MGC126025|Lymphocyte activation gene 1|Small inducible cytokine A4|Secreted protein G26|MIP-1 Beta|SCYA4|ACT 2|HC21|MGC104418|CC chemokine ligand 4|PAT 744|AT744.1|CCL4_MOUSE|SCYA2|Secreted protein G 26|MGC126026|CCL4|MIP1 beta|G 26 T lymphocyte secreted protein|Macrophage inflammatory protein 1 beta|ACT2|Macrophage Inflammatory Protein 1 beta|Lymphocyte activation gene 1 protein|Chemokine CC Mot Ligand 4|LAG 1|CCL4L1|Protein H400|MIP1B|ccl4l 1|MIP1B1|SIS gamma|LAG1|T cell activation protein 2
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Molecular Weight:7.8 kDa
- Storage Temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from mouse CCL4
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76081-788
- Packaging:Vial
Specifications
About this item
MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD 5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor 1 (CC CKR1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.
Type: Primary
Antigen: CCL4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 26-92/92
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rabbit