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Anti-KCNQ1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-KCNQ1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # 76118-702
Supplier:  Bioss
Anti-KCNQ1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # 76118-702
Supplier:  Bioss
Supplier Number:  BS-6760R-A750

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    KCNQ1
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rat
  • Western Blot:
    Yes
  • Size:
    100 µl
  • Epitope:
    501-600/676
  • Form:
    Liquid
  • Gene ID:
    3784
  • Antigen Synonyms:
    KQT-like 1|Kv7.1|JLNS1|KCNQ1|ATFB3|WRS|ATFB1|SQT2|LQT1|Voltage-gated potassium channel subunit Kv7.1|LQT|Kv1.9|KCNA8|IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1|KVLQT1|Potassium voltage-gated channel subfamily KQT member 1|RWS|KCNA9
  • Modification:
    Unmodified
  • Storage Buffer:
    Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
  • Molecular Weight:
    75 kDa
  • Storage Temperature:
    Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping Temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human KCNQ-1
  • Tested Applications:
    ICC
  • Purification:
    Purified by Protein A
  • Cat. No.:
    76118-702
  • Packaging:
    Vial

Specifications

About this item

Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.

Type: Primary
Antigen: KCNQ1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 501-600/676
Host: Rabbit
Isotype: IgG
Reactivity: Rat