Specifications
- Antibody Type:Primary
- Antigen Name:KCNQ1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat
- Western Blot:Yes
- Size:100 µl
- Epitope:501-600/676
- Form:Liquid
- Gene ID:3784
- Antigen Synonyms:KQT-like 1|Kv7.1|JLNS1|KCNQ1|ATFB3|WRS|ATFB1|SQT2|LQT1|Voltage-gated potassium channel subunit Kv7.1|LQT|Kv1.9|KCNA8|IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1|KVLQT1|Potassium voltage-gated channel subfamily KQT member 1|RWS|KCNA9
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- Molecular Weight:75 kDa
- Storage Temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human KCNQ-1
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76118-702
- Packaging:Vial
Specifications
About this item
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
Type: Primary
Antigen: KCNQ1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 501-600/676
Host: Rabbit
Isotype: IgG
Reactivity: Rat