About this item
This antibody recognizes a protein of 25-26kDa, identified as bcl-2 alpha oncoprotein. It shows no cross-reaction with BCL-X or BAX protein. Expression of BCL-2 alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. This antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express BCL-2 protein and small number in which neoplastic cells are BCL-2 negative.
To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.
Specifications
- Catalog No:
- 76633-102
- 76633-100
- 76633-098
- Antigen Name:
- BCL-2 oncoprotein
- BCL-2 oncoprotein
- BCL-2 oncoprotein
- Antibody Type:
- Primary
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Monoclonal
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Clone:
- 124
- 124
- 124
- Reactivity:
- Human
- Human
- Human
- Host:
- Mouse
- Mouse
- Mouse
- Isotype:
- IgG1 kappa
- IgG1 kappa
- IgG1 kappa