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Specifications
- Antibody Type:Primary
- Antigen Name:Adipocyte Fatty Acid Binding Protein
- Antigen Symbol:A-FABP
- Clonality:Polyclonal
- Clone:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Goat
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Western Blot:Yes
- Size:0.1 mg
- Form:The antibody is lyophilized in 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE.
- Antigen Synonyms:ALBP|A-FABP|Fatty acid-binding protein 4|FABP4|Adipocyte lipid-binding protein|Adipocyte-type fatty acid-binding protein
- Storage Buffer:Add 0.2 ml of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
- Shipping Temperature:At ambient temperature
- Purification:Immunoaffinity chromatography on a column with immobilized recombinant Human FABP4.
- Cat. No.:101076-790
- Supplier no.:RD184037100
Specifications
About this item
Quality control test, Indirect ELISA – to determine titer of the antibody , SDS PAGE – to determine purity of the antibody, and BCA - to determine quantity of the antibody.
Adipocyte fatty acid binding protein AFABP is a 15 kDa member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids) in an internal cavity. AFABP is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells . In mice, targeted mutations in AFABP provide significant protection from hyperinsulinemia and insulin resistance in the context of both dietary and genetic obesity. Adipocytes obtained from AFABP-deficient mice also have reduced efficiency of lipolysis in vitro and in vivo, and these mice exhibited moderately improved systemic dyslipidemia. Recent studies also demonstrated AFABP expression in macrophages upon differentiation and activation.
Storage temperature: The lyophilized antibody remains stable and fully active until the expiry date when stored at –20 °C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at –80 °C. Reconstituted antibody can be stored at 4 °C for a limited period of time; it does not show decline in activity after one week at 4 °C.