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Specifications
- Antibody Type:Primary
- Antigen Name:Epidermal Fatty Acid Binding Protein
- Antigen Symbol:E-FABP
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Size:0.1 mg
- Shipping Temperature:At ambient temperature
- Purification:Immunoaffinity chromatography on a column with immobilized recombinant Human FABP5
- Cat. No.:101215-318
- Packaging:Glass ampoule
- Supplier no.:RD181060100
Specifications
About this item
Good for research into cardiovascular disease, Diabetology - Other Relevant Products, Energy metabolism and body weight regulation and Oncology. The immunization antigen (15.2 kDa) is a protein containing 135 AA of recombinant Human FABP5 and one extra AA, Nterminal methionine (highlighted).
- Raised in rabbits by immunization with the recombinant Human FABP5
- 0.1 mg (determined by BCA method, BSA was used as a standard)
- lyophilized in 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
Human fatty acid binding protein EFABP is a 15 kD member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to bind fatty acids and related compounds ( bile acids or retinoids). in an internal cavity. The fatty acid binding proteins aP2 (fatty acid binding protein [FABP]-4) and mal1 (EFABP) are closely related and both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systemic insulin sensitivity.
For reconstitution, add 0.2 ml of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
The lyophilized antibody remains stable and fully active until the expiry date when stored at −20 °C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles and store frozen at −80 °C. Reconstituted antibody can be stored at 4 °C for a limited period of time; it does not show decline in activity after one week at 4 °C.