Bond Elut SI can be used to separate compounds with highly similar structures.

• Highly polar phase retains polar molecules from nonpolar matrices
• High-purity silica
• Separate compounds with very similar structures

Bond Elut SI is a very polar sorbent and is particularly effective at separating compounds with a very similar structure. Applying the analytes in a nonpolar solvent, then increasing the solvent polarity by increasing the concentration of a polar modifier, such as THF or ethyl acetate, delivers effective separations.