A lower priced, turnkey replacement for your SPRI beads.
- Drop-in replacement for SPRI beads resulting in no protocol changes
- RNAse-free certified for purifcation of both RNAand DNA from same kit
- Uniformly-sized paramagnetic beads for highly reproducible results
- Paramagnetic beads
The CleanNGS kit offers a highly efficient magnetic bead-based cleanup system for the purification of both DNA and RNA for Next-Generation Sequencing and Sanger Sequencing workflows. This kit can perform both library clean-up and size selection functions. It is a direct replacement for more expensive SPRI (Solid Phase Reversible Immobilization)-based bead options. The nucleic acid cleanup protocol is a simple 4-step protocol that is completely automatable and totally reliable.
These beads disperse and float in solution as long as–or longer than any other commercially available beads. The paramagnetic beads have been designed specifically to improve separation and migration to and from the magnet, shortening the processing time and improving separation results. This ensures consistently high yields and no contaminants.
Using SPRI beads for size selection is a finely-tuned protocol based upon ethanol concentration. The CleanNGS Kit has perfectly formulated solutions so that size selection is always tight and consistent. Left, right, or double-sized size selection can be performed due to the stable buffer system. The CleanNGS kit has been compared by several European labs and the results are ALWAYS POSITIVE — similar (or better) size selection and purity as compared to the other top SPRI beads. That means your lab will NOT need to reoptimize; just use the exact same protocol, whether with a robot or by hand. It’s that easy.
The CleanNGS kit is ideal for automation of sample cleanup for NGS applications. Automation of the CleanNGS protocol can be done on liquid handling platforms of most common brands. Programming the liquid handler can be done by GC biotech, eliminating difficulties during the transfer and ensuring a fully automated purification on your existing setup.