Unconjugated

Recombinant

HEK293 cells

Cynomolgus monkey

–20 °C

Less than 1.0 EU per μg by the LAL method.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.; Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus LDL R, His Tag (Cat. No. LDR-C5222) at 2 μg/mL (100 μL/well) can bind Biotinylated Human PCSK9, Avitag,His Tag (Cat. No. PC9-H82E7) with a linear range of 0.007-0.256 μg/mL (QC tested).; Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus PCSK9, His Tag (Cat. No. PC9-C5223) at 10 μg/mL (100 μL/well) can bind Cynomolgus LDL R, His Tag (Cat. No. LDR-C5222) with a linear range of 0.04-0.256 μg/mL (Routinely tested).; Loaded Human PCSK9, Fc Tag (Cat. No. PC9-H5256) on Protein A Biosensor, can bind Cynomolgus LDL R, His Tag (Cat. No. LDR-C5222) with an affinity constant of 1.24 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Y

Y

Y

FHC|LDLR|FH|LDLCQ2

LDL R

>95%

86.8 kDa

Low

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Y

Powder,RT