Human Recombinant FGF-7/KGF (from E. coli)
Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
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About this item
Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb). The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells. FGF-7 also induces the formation of the apical ectodermal ridge during limb development.
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- Low endotoxin
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Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:–20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity Assay: 4MBr-5 cell proliferation, ED₅₀ ≤60 ng/ml, Bioactivity ≥1.7×10⁴ units/mg
- Gene ID:P21781
- Reconstitution Instructions:Sterile water at 0.1 mg/ml (reconstitution at concentrations > 0.1 mg/ml may result in a precipitate)
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein Synonyms:KGF
- Protein/Peptide Name:FGF-7 / KGF (AF)
- Purity:≥90%
- Molecular Weight:19 kDa
- Sequence:MACNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
- Endotoxin Level:Low
- Formulation:20 mM Sodium phosphate, 0.5 M Sodium chloride, pH 7.5
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay