About this item
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.
- High quality
- Low endotoxin
- Affordable
Animal-free proteins are ideal for researchers concerned about the ever-present risk of contaminating human proteins or trace growth factors from FBS and animal-derived ingredients typically used in standard recombinant protein production techniques.
To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Dog
- Storage Conditions:−20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity assay: TF-1 cell proliferation, ED50 ≤15 ng/ml, bioactivity ≥6.7×10⁴ units/mg
- Gene ID:P48749
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:Y
- Protein Synonyms:MGI-1GM|CSF-2|Pluripoietin-α
- Protein/Peptide Name:RC GM-CSF (AF)
- Purity:≥95%
- Molecular Weight:14.4 kDa
- Sequence:MAPTRSPTLV TRPSQHVDAI QEALSLLNNS NDVTAVMNKA VKVVSEVFDP EGPTCLETRL QLYKEGLQGS LTSLKNPLTM MANHYKQHCP PTPESPCATQ NINFKSFKEN LKDFLFNIPF DCWKPVKK
- Endotoxin Level:Low
- Formulation:10 mM sodium phosphate, pH 7.5
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay