Rat Recombinant VEGF (from E. coli)
Catalog # 76303-878
Supplier: Peprotech
CAS Number:
Specifications
- Conjugation:Unconjugated
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Rat
- Size:50 µg
- Biological Activity:Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0-8.0 ng/ml.
- Gene ID:83785
- Animal-Free:Y
- Protein Synonyms:VEGF-A|Glioma-derived endothelial cell mitogen|Folliculostellate cell-derived growth factor|Vascular Endothelial Growth Factor
- Protein/Peptide Name:VEGF
- Purity:98%
- Molecular Weight:38.5 kDa
- Sequence:MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
- Endotoxin Level:Low
- Formulation:Lyophilized
- Shipping Temperature:Ambient
- Cat. No.:76303-878
Specifications
About this item
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Rat VEGF 165 is a 38.5 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.