Human Recombinant IL-5 (from E. coli)

About this item

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 are cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.

Animal-free

Specifications

Conjugation:
Unconjugated
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Biological Activity:
The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 0.15 ng/ml, corresponding to a specific activity of ≥ 6.6 x 10^6 units/mg.
Gene ID:
3567
Animal-Free:
Y
Protein Synonyms:
Interleukin-5|EDF|TRF|BCDFII
Protein/Peptide Name:
IL-5
Purity:
98%
Molecular Weight:
26.5 kDa
Sequence:
MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
Endotoxin Level:
Low
Formulation:
Lyophilized
Shipping Temperature:
Ambient