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Human Recombinant GDF-3 (from E. coli)
Human Recombinant GDF-3 (from E. coli)
Catalog # 76303-592
Supplier:  Peprotech
CAS Number:  
Human Recombinant GDF-3 (from E. coli)
Catalog # 76303-592
Supplier:  Peprotech
Supplier Number:  AF-120-22-50UG
CAS Number:  

Specifications

  • Conjugation:
    Unconjugated
  • Protein/Peptide Type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    50 µg
  • Biological Activity:
    Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/ml.
  • Gene ID:
    9573
  • Animal-Free:
    Y
  • Protein Synonyms:
    Vgr-2|Growth/Differentiation Factor-3|UNQ2222/PRO248
  • Protein/Peptide Name:
    GDF-3
  • Purity:
    98%
  • Molecular Weight:
    26 kDa
  • Sequence:
    AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
  • Endotoxin Level:
    Low
  • Formulation:
    Lyophilized
  • Shipping Temperature:
    Ambient
  • Cat. No.:
    76303-592

Specifications

About this item

GDF-3 is a member of the TGF-beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes. Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.

  • Animal-free