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Human;Mouse;Rat Recombinant BDNF (from E. coli)
Human;Mouse;Rat Recombinant BDNF (from E. coli)
Catalog # 76303-662
Supplier:  Peprotech
CAS Number:  
Human;Mouse;Rat Recombinant BDNF (from E. coli)
Catalog # 76303-662
Supplier:  Peprotech
Supplier Number:  AF-450-02-50UG
CAS Number:  
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Specifications

  • Conjugation:
    Unconjugated
  • Protein/Peptide Type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
    Rat
    Mouse
  • Size:
    50 µg
  • Environmentally Preferable:
  • Biological Activity:
    Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 ug/ml.
  • Gene ID:
    627
  • Animal-Free:
    Y
  • Protein Synonyms:
    Brain Derived Neurotrophic Factor|Abrineurin
  • Protein/Peptide Name:
    BDNF
  • Purity:
    98%
  • Molecular Weight:
    27 kDa
  • Sequence:
    MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
  • Endotoxin Level:
    Low
  • Formulation:
    Lyophilized
  • Shipping Temperature:
    Ambient
  • Cat. No.:
    76303-662

Specifications

About this item

BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human/Murine/Rat BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.

  • Animal-free