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Human Recombinant FcRn (FCGRT & B2M) (from HEK293 cells), Biotin
Human Recombinant FcRn (FCGRT & B2M) (from HEK293 cells), Biotin
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Human Recombinant FcRn (FCGRT & B2M) (from HEK293 cells), Biotin
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* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.

Specifications

  • Conjugation:
    Biotin
  • Protein/Peptide Type:
    Recombinant
  • Source:
    HEK293 cells
  • Species:
    Human
  • Storage Conditions:
    –20 °C
  • Endotoxin Content:
    Less than 1.0 EU per μg by the LAL method.
  • Biological Activity:
    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.; Measured by its binding ability in a functional ELISA. Immobilized Ipilimumab at 10 μg/mL (100 μL/well) can bind Biotinylated Human FcRn Heterodimer Protein (primary amine labeling) (Cat. No. FCM-H8286) with a linear range of 5-78 ng/mL (QC tested).; Immobilized Biotinylated Human FcRn Heterodimer Protein (primary amine labeling) (Cat. No. FCM-H8286) on SA Biosensor, can bind Herceptin with an affinity constant of 0.49 μM as determined in BLI assay (Fortebio Octet 96) (Routinely tested).
  • Protease-free:
    Y
  • Animal-Free:
    Y
  • Protein Synonyms:
    FcRn|FCGRT & B2M
  • UniProtKB:
    P55899 (FcRN) & P61769 (B2M)
  • Protein/Peptide Name:
    FcRn (FCGRT & B2M)
  • Purity:
    >95% as determined by SDS-PAGE.
  • Molecular Weight:
    31.2 kDa (FCGRT), 13.1 kDa (B2M)
  • Endotoxin Level:
    Low
  • Formulation:
    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
  • Shipping Temperature:
    Powder,RT

Specifications