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Specifications
- Antibody Type:Primary
- Antigen Symbol:STAT5A
- Clonality:Polyclonal
- ELISA:Yes
- Host:Rabbit
- Isotype:
- Reactivity:Rabbit
- Western Blot:Yes
- Size:100 µg
- Environmentally Preferable:
- Modification:Methylation
- Storage Temperature:Store vial at –20 °C. Aliquot contents and freeze at –20 °C. Centrifuge product if not completely clear after standing at room temperature. Stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
- Shipping Temperature:Dry Ice
- Purification:Affinity purified
- Cat. No.:75932-214
- Supplier no.:600-401-GH4
Specifications
About this item
Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a and Stat5b. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.
Anti-STAT5 [Arg31/Me1] antibody is useful for Western Blot and Dot Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~90.6 kDa corresponding to STAT5 protein by Western Blotting in the appropriate cell lysate or extract.
Type: Primary
Antigen: STAT5A
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Rabbit