Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord. Anti-Neuroligin-1 is ideal for research in Neuroscience, including narcolepsy and synaptic neurotransmission: GABAergic inhibition, as well as Cell Adhesion.

Anti-Neuroligin 1 R-PE Conjugated Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~120kDa on specific lysates or tissues. Does not cross react with other Neuroligins. Specific conditions for reactivity should be optimized by the end user.

Type: Primary
Antigen: Neuroligin-1
Clonality: Monoclonal
Clone: S97A-31
Conjugation: RPE
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: