HSD17B10 control protein-GST fusion

• Control Protein
• PCA Assays
• ImmunoBlot

HSD17B10 gene encodes the protein 17-beta-hydroxysteroid dehydrogenase 10 that is a member of the short-chain dehydrogenase/reductase superfamily SCHAD (1). HSD17B10 gene product is a mitochondrial protein that is involved in lipid metabolism, fatty acid oxidation and steroid hormone metabolism. HSD17B10 protein has been implicated in the development of Alzheimer's disease and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Furthermore, HSD17B10 may act as a direct molecular link between beta-amyloid and mitochondrial toxicity (2). HSD17B10 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Cellular Stress, and Neurobiology research.

HSD17B10 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. HSD17B10 Protein is suitable for use in Western Blot. Expect a band approximately ~51kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.