Human Recombinant BCKDK (from Baculovirus (Sf9 Insect cells))

BCKDK or branched chain alpha-keto acid dehydrogenase kinase is an important regulator of the valine, leucine, and isoleucine catabolic pathways. BCKDK is found in the mitochondrion where it phosphorylates and inactivates BCKD. The branched-chain alpha-keto dehydrogenase complex (BCKDH) catalyzes the rate-limiting step in the oxidation of branched-chain amino acids and BCKDK inactivates the BCKDH complex by catalyzing serine phosphorylation of the E1-alpha subunit (1). BCKDH kinase catalyzes the serine phosphorylation of the E1- alpha subunit of BCKDH (2). BCKDK Protein is ideal for investigators involved in Singaling Proteins, Cellular Proteins, and Metabolic Disorder research.

Protein/Peptide Type:
Recombinant
Source:
Baculovirus (Sf9 Insect cells)
Species:
Human
Storage Conditions:
Store product at –70 °C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Protein Synonyms:
[BCKDKD|BCKD-kinase|BCKDHKIN|3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase|mitochondrial|Branched-chain alpha-ketoacid dehydrogenase kinase|BDK
Protein/Peptide Name:
BCKDK
Purity:
>95%
Formulation:
Liquid (sterile filtered)
Shipping Temperature:
Dry Ice