Human Recombinant IL-10 (from E. coli)
76077-474
:
- Conjugation:Unconjugated
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Size:1 mg
- Storage Conditions:Store at –20 °C prior to reconstitution.
- Endotoxin Content:>0.1 ng/μg
- Biological Activity:Biological Activity tests can vary. Please refer to the Product CoA for information.
- Form:Lyophilized
- Gene ID:3586 P22301
- Reconstitution Instructions:Reconstitution instructions can vary. Please refer to the product CoA for info.
- Protease-free:Y
- Animal-Free:Y
- Protein Synonyms:B-TCGF|TGIF|Interleukin-10|CSIF
- Protein/Peptide Name:IL-10
- Purity:0.98
- Molecular Weight:18.6 kDa
- Sequence:MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
- Endotoxin Level:Low
- Formulation:Formulation can vary. Please refer to product CoA for information.
- Shipping Temperature:Ambient
- Cat. No.:76077-474
- Animal-free
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-α. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Human IL-10 is an 18.6 kDa protein of 161 amino acid residues.