About this item
This antibody recognizes five invariable CD3 chains (designated as and ) with molecular weight ranging from 16-28 kDa. CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Type: Primary
Antigen: CD3E
Clonality: Monoclonal
Clone: B-B12
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.
Specifications
- Catalog No:
- 75895-366
- 75895-368
- Antigen Symbol:
- CD3E
- CD3E
- Antigen Name:
- CD3e
- CD3e
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 488A
- CF® 488A
- Clone:
- B-B12
- B-B12
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 3003
- Unigene ID: 3003
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0.1 mg/ml
- 0.1 mg/ml
- Storage Buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide