This MAb reacts with a protein of 20-30 kDa, identified as PGP 9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1). Initially, PGP 9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP 9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP 9.5 gene is believed to cause a form of Parkinson's disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Type: Primary
Antigen: UCHL1
Clonality: Monoclonal
Clone: Clone UCHL1/841
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human