About this item
This antibody recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma ( ) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Type: Primary
Antigen: CD5
Clonality: Monoclonal
Clone: Clone CD5/54/F6
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Chicken, Cow, Guinea Pig, Horse, Human, Monkey, Pig, Rabbit, Rat
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Specifications
- Catalog No:
- 75915-004
- 75915-006
- Antigen Symbol:
- CD5
- CD5
- Antigen Name:
- CD5
- CD5
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 640R
- CF® 640R
- Clone:
- CD5/54/F6
- CD5/54/F6
- Reactivity:
- Pig, Rabbit, Horse, Monkey, Chicken, Human, Bovine, Guinea pig, Rat
- Pig, Rabbit, Horse, Monkey, Chicken, Human, Bovine, Guinea pig, Rat
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 58685
- Unigene ID: 58685
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0.1 mg/mL
- 0.1 mg/mL
- Storage Buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide