About this item
This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®680R is a near-infrared fluorescent dye (Ex/Em 680/701 nm) with unrivaled photostability. It also is validated in super-resolution imaging by STED and single-molecule spectroscopy.
Type: Primary
Antigen: MLANA
Clonality: Monoclonal
Clone: Clone M2-9E3
Conjugation: CF680R
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human, Mouse, Rat
Specifications
- Catalog No:
- 75960-534
- 75960-532
- Antigen Symbol:
- MLANA
- MLANA
- Antigen Name:
- Melan-A
- Melan-A
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 680R
- CF® 680R
- Clone:
- M2-9E3
- M2-9E3
- Reactivity:
- Human, Rat, Mouse
- Human, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 154069
- Unigene ID: 154069
- Isotype:
- IgG2b kappa
- IgG2b kappa
- Western Blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Concentration:
- 0.1 mg/mL
- 0.1 mg/mL
- Storage Buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide