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Specifications
- Description:S-Adenosyl-L-homocysteine (SAH) ELISA Assay Kit
- Size:1 kit
- Cat. No.:102994-926
- Supplier no.:SAH31-K01
Specifications
About this item
S-Adenosyl-L-homocysteine (SAH) ELISA is intended to detect SAH in serum or plasma.
- Dynamic Range: 31.25 - 1000 nM
- Sensitivity: 31.25 nM
- Incubation: 1.5 hours
Methionine is an amino acid with sulfur methyl group, which is converted into S-adenosylmethionine (SAM) with ATP by methionine adenosyltransferase (EC 2.5.1.6). SAM is the sole methyl group donor for over 50 kinds of biologically active substances such as DNA, RNA, protein, phospholipids, hormones and neuro-transmitters, etc. After methyl group is transferred away from SAM under a mehtyltransferase, S-adenosylhomocysteine is formed, which is further metabolized into homocysteine (Hcy) after adenosine is removed. The homocysteine is metabolized to methionine through N5-methyl tetrahydrofolate methyltransferase (EC1.1.1.68) and coenzyme vitamin B12 catalytic pathway accepting methyl from N5-methyltetrahydrofolate. This is methionine cycle.