Specifications
- Antibody Type:Primary
- Antigen Name:Calnexin Antibody [CANX/1541]
- Antigen Symbol:CNX
- Clonality:Monoclonal
- Clone:CANX/1541
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG2b kappa
- Reactivity:Human
- Western Blot:Yes
- Size:100 ug
- Format:Purified Antibody
- Form:Liquid
- Storage Buffer:PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- Storage Temperature:Aliquot and Store at 2…8 °C. Avoid freez-thaw cycles.
- Concentration:0.2 mg/mL
- Shipping Temperature:4 °C
- Immunogen:A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
- Purification:Protein G affinity chromatography
- Cat. No.:76194-400
Specifications
About this item
It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
WB: 0.5-1 ug/ml Flow Cytometry: 0.5-1ug/10^6 cells Immunofluorescence: 0.5-1 ug/ml Immunohistochemistry (FFPE): 1-2 ug/ml for 30 min at RT Titering of the Calnexin antibody may be required for optimal performance.
Type: Primary
Antigen: Calnexin Antibody [CANX/1541]
Clonality: Monoclonal
Clone: CANX/1541
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human