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- Antibody Type:Primary
- Antigen Name:T-cell immunoglobulin and mucin-domain containing-3
- Antigen Symbol:TIM3
- Clonality:Monoclonal
- Clone:F38-2E2
- Conjugation:APC (Allophycocyanin)
- Flow Cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Size:25 tests
- Environmentally Preferable:
- Form:liquid
- Antigen Synonyms:KIM-3|TIMD-3|TIMD3|HAVcr-2|Tim-3|hepatitis A virus cellular receptor 2|TIM3|CD366
- Cat. No.:75844-516
- Supplier no.:78211-80-25
The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17. TIM3 can exist in soluble and membrane bound forms and the relevant ligand for the protein is Galectin-9. It plays a role in the creation of immunological tolerances, the secretion of Th1 and Th17 related cytokines, and HIV infection.
Type: Primary
Antigen: TIM3
Clonality: Monoclonal
Clone: F38-2E2
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human