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Specifications
- Antibody Type:Primary
- Antigen Name:MHC Class II
- Antigen Symbol:MHC Class II
- Clonality:Monoclonal
- Clone:M5/114.15.2
- Conjugation:BG Violet 450
- Flow Cytometry:Yes
- Host:Rat
- Isotype:IgG2b kappa
- Reactivity:Mouse
- Size:25 μg
- Environmentally Preferable:
- Form:liquid
- Antigen Synonyms:MHC II|MHC class II|IA|IE|I-A/E
- Cat. No.:75841-438
- Supplier no.:86212-40-25
Specifications
About this item
The M5/114.15.2 monoclonal antibody or (M5/114) is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins (alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens). The antibody also reacts with cells from the H-2p or H-2r haplotypes mice. The polymorphic determinant represented by the mouse major histocompatibility complex class II (MHC Class II) is expressed by the immune cells bearing the specified alloantigens, like T and B lymphocytes, monocytes, dendritic cells, and macrophages. The antibody doesn’t react with the NOD H-2g7 haplotype alloantigens. M5/114 mAb inhibits I-A-restricted T cell responses of the Haplotypes H-2b, H-2d, H-2q, and H-2u. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
Type: Primary
Antigen: MHC Class II
Clonality: Monoclonal
Clone: M5/114.15.2
Conjugation: BG Violet 450
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse