Anti-Foxp3 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: 3G3]
75842-608
- Antibody Type:Primary
- Antigen Name:Foxp3 (3G3)
- Antigen Symbol:Foxp3
- Clonality:Monoclonal
- Clone:3G3
- Conjugation:APC (Allophycocyanin)
- Flow Cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Mouse
- Size:25 μg
- Form:liquid
- Antigen Synonyms:Zinc finger protein JM2|JM2|Forkhead box protein P3|Scurfin|IPEX
- Cat. No.:75842-608
- Supplier no.:83412-80-25
The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the “scurfy†mice phenotype.
Type: Primary
Antigen: Foxp3
Clonality: Monoclonal
Clone: 3G3
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Mouse