The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+,CD48-, and CD41- can be used to identify hematopoietic stem cells.

Type: Primary
Antigen: CD41
Clonality: Monoclonal
Clone: MWReg30
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG1, kappa
Reactivity: Mouse