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- Antibody Type:Primary
- Antigen Symbol:CD117
- Clonality:Monoclonal
- Clone:ACK2
- Conjugation:APC (Allophycocyanin)
- Flow Cytometry:Yes
- Host:Rat
- Isotype:IgG2b kappa
- Reactivity:Mouse
- Size:100 μg
- Environmentally Preferable:
- Form:liquid
- Antigen Synonyms:SCFR|cKit|Steel Factor Receptor
- Cat. No.:75844-446
- Supplier no.:19112-80-100
The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
Type: Primary
Antigen: CD117
Clonality: Monoclonal
Clone: ACK2
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Rat
Isotype: IgG2b, kappa
Reactivity: Mouse